12 results
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
CNS Ring-Enhancing ... + toxo IgG • CNS ... 30% present w/ CNS ... histoplasmosis, cryptococcus ... RingEnhancing #Lesions #Brain
Differential Diagnosis for Concurrent Brain and Lung Infections
 • Bacteria: Strep anginosus, Staph aureus, Klebsiella pneumoniae
Diagnosis for Concurrent ... Brain and Lung ... Mucormycosis, Cryptococcus ... @ID_fellows #Brain ... Lung #Infections #Concurrent
Concurrent Brain and Lung Lesions
 • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
Concurrent Brain ... Mucormycosis, Cryptococcus ... febrilepodcast #Brain ... Lung #Infections #Concurrent
Concurrent Brain and Lung Lesions
 • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
Concurrent Brain ... Mucormycosis, Cryptococcus ... febrilepodcast #Brain ... Lung #Infections #Concurrent
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
CNS Infection in ... HIV-Associated CNS ... should be based on clinical ... culture positive Cryptococcal ... lesions • CSF cryptococcal
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
- Negative: Cryptococcus ... cut-offs defined in clinical ... Paecilomyces, Cryptococcus ... decreased with: concurrent
Hemiballismus on Physical Exam secondary to Cryptococcal fungal infection
MRI showed 2 pockets of infection on both
Exam secondary to Cryptococcal ... both sides of his brain ... #PhysicalExam #clinical
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
Fluconazole CRYPTOCOCCUS ... MC: CNS CSF: • ... level, presence of cryptococcal ... CSF and serum Cryptococcal ... • Sinusitis • Brain
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
initiation Clinical ... pleural effusions, CNS ... cavitation • Cryptococcus ... patient has known cryptococcal ... for most OI • Cryptococcal
Invasive Fungal Infection (IFI)

Invasive fungal infections are severe infections in which fungal pathogens invade normally sterile
pulmonary infections) Cryptococcus ... species (commonly CNS ... antibiotic exposure Clinical ... galactomannan, cryptococcal