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diagnosis causes infections infectiousdiseases fungal abscess aspergillus betadglucan biomarkers cardiology cns comparison endocarditis galactomannan lesions mycoses neurology pulmonary radiology ringenhancing
Differential Diagnosis for Concurrent Brain and Lung Infections • Bacteria: Strep anginosus, Staph aureus, Klebsiella pneumoniae
Differential Diagnosis ... for Concurrent ... Brain and Lung Infections ... Mucormycosis, Cryptococcus ... #Concurrent #Differential
Concurrent Brain and Lung Lesions • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
Concurrent Brain ... and Lung Lesions ... Mucormycosis, Cryptococcus ... #Lung #Infections ... #Concurrent #Differential
Concurrent Brain and Lung Lesions • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
Concurrent Brain ... and Lung Lesions ... Mucormycosis, Cryptococcus ... #Lung #Infections ... #Concurrent #Differential
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
lesions • 80% with lung ... histoplasmosis, cryptococcus ... RingEnhancing #Lesions #Brain ... #differential #
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
and Management ... Abscess Management ... Dermatitidis - Cryptococcus ... Abscess Differential ... Abscess #pulmonary #differential
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
- Negative: Cryptococcus ... Paecilomyces, Cryptococcus ... BAL GM does not differentiate ... decreased with: concurrent ... Clav (may be + as long
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
Fluconazole CRYPTOCOCCUS ... level, presence of cryptococcal ... CSF and serum Cryptococcal ... • Sinusitis • Brain ... Fungal #Diagnosis #Management
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
verrucous) • Lung ... Aspergillus • Cryptococcus ... Marantic (NTBE) Differential ... Endocarditis #diagnosis #management
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