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diagnosis ctchest radiology radiologyassistant fungal hrct differential infectiousdiseases microbiology infections nodular pathology atlas betadglucan biomarkers cystic fungi galactomannan highattenuation lowattenuation
Fungal Pneumonias - Diagnosis Comparison Table • Aspergillus • Blastomyces • Candida • Coccidioides • Cryptococcus
Pneumonias - Diagnosis Comparison ... Table • Aspergillus ... Coccidioides • Cryptococcus ... Pneumonias #Diagnosis #Comparison ... #Table #microbiology
Important Fungal Stains Mycology Lab: • Calcofluor white - Fluorochrome that binds glucans and chitin in fungal
exceptions are Aspergillus ... polysaccharide capsule of Cryptococcus ... detection for cryptococcal ... mucopolysaccharide capsule of Cryptococcus ... #table
Fungal Biomarkers: Comparing Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi •
Beta-D-Glucan and Aspergillus ... Spec ~77-96% Aspergillus ... constituent of Aspergillus ... Paecilomyces, Cryptococcus ... Galactomannan #diagnosis #comparison
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
Beta-D-Glucan and Aspergillus ... - Negative: Cryptococcus ... cut-offs defined in clinical ... Paecilomyces, Cryptococcus ... Galactomannan #diagnosis #comparison
Morphology and Descriptions of Endemic Fungal Infections with Yeasts in Tissues Broad-based budding yeasts: • Description: Broad-based
, Histoplasma, Cryptococcus ... , and Aspergillus ... Consistent with Cryptococcus ... capsule deficient Cryptococcus ... yeasts #pathology #clinical
Common Fungal Pathology • Candida - Small yeast intermingled with pseudohyphae • Aspergillosis - Septate
broad based bud • Cryptococcus ... Fungal #Pathology #clinical ... #microscopy #table ... #atlas #key #comparison
Antifungal Echinocandins - Antibiotics Class Overview Mechanism: Inhibit glucan synthesis in fungal cell wall by blocking
usually works clinically ... Static vs Aspergillus ... > 2nd-line for Aspergillus ... lack activity vs Cryptococcus
Low Attenuation pattern 1. Lymphangiomyomatosis (LAM): uniform cysts in woman of child-bearing age; no history of
Low Attenuation pattern ... #Clinical #Radiology ... LowAttenuation #Cystic #Pattern ... #Comparison #Table
Nodular pattern 1. Hypersensitivity pneumonitis: ill defined centrilobular nodules. 2. Miliary TB: random nodules 3. Sarcoidosis: nodules with perilymphatic
Nodular pattern ... #Clinical #Radiology ... CTChest #Nodular #Pattern ... #Comparison #Table
High Attenuation pattern 1. Chronic eosinophilic pneumonia with peripheral areas of ground glass opacity. 2. Sarcoid end-stage
High Attenuation pattern ... consolidation #Clinical ... HighAttenuation #Pattern ... #Comparison #Table
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