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IDSA Treatment Recommendations for Cryptococcal Meningoencephalitis - Induction, Consolidation and Maintenance Therapy

Table 2. Antifungal Treatment Recommendations
Recommendations for Cryptococcal ... Recommendations for Cryptococcal ... Recommendations for Cryptococcal ... IDSA #Treatment #management ... #meningitis #cryptococcus
IDSA Treatment Recommendations for Cryptococcal Meningoencephalitis in Transplant Recipients
Induction therapy:
 • liposomal AmB (3–4 mg/kg per
Recommendations for Cryptococcal ... year B-III #Cryptococcal ... IDSA #Treatment #management ... #meningitis #cryptococcus
IDSA Treatment Recommendations for Cryptococcal Meningoencephalitis in Human Immunodeficiency Virus Infected Individuals
Induction therapy:
 • AmBd (0.7–1.0
Recommendations for Cryptococcal ... week) >1 year #Cryptococcal ... IDSA #Treatment #management ... #meningitis #cryptococcus
Initiation of ART in HIV patients with Opportunistic Infections
 • Pulmonary TB and CD4 cell count
regardless of CD4 • Cryptococcal ... Meningitis • ... Opportunistic #Infections #management
Flutycosine - Antibiotics Class Overview
 - 
Mechanism: 5-FC interferes with DNA and protein synthesis.  Only
B for initial management ... infections: Severe cryptococcal ... pneumonia and meningitis ... (endocarditis, meningitis
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
cavitation • Cryptococcus ... patient has known cryptococcal ... for most OI • Cryptococcal ... meningitis: ART ... Differential #Diagnosis #Management
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
Fluconazole CRYPTOCOCCUS ... level, presence of cryptococcal ... CSF and serum Cryptococcal ... infection (~40%) • Meningitis ... Fungal #Diagnosis #Management
Important Fungal Stains
Mycology Lab:
 • Calcofluor white - Fluorochrome that binds glucans and chitin in fungal
polysaccharide capsule of Cryptococcus ... detection for cryptococcal ... meningitis; some ... mucopolysaccharide capsule of Cryptococcus ... cell walls of Cyptococcus
Papilledema on Fundoscopy Ocular Examination

Papilledema in a patient with cryptococcal meningitis

Dr. Sebastian Vega @oftalmopo

#Papilledema #cryptococcus #meningitis
a patient with cryptococcal ... meningitis Dr ... #Papilledema #cryptococcus ... #meningitis #Ocular
Cryptococcus neoformans - One Page Diagnosis and Management Summary

Dr. Lizzy Hastie @LizzyHastie

#Cryptococcus #neoformans #Diagnosis #Management #Treatment
Cryptococcus neoformans ... Diagnosis and Management ... @LizzyHastie #Cryptococcus ... neoformans #Diagnosis #Management