11 results
Laboratory Testing in Hemolytic Anemia

Intravascular vs Extravascular Hemolysis
Reticulocytes
Unconjugated bilirubin
LDH
Peripheral smear
Haptoglobin
Urine hemosiderin
Urine hemoglobin
Carboxyhemoglobin

#Hemolytic #Anemia #Laboratory #Testing #workup
Laboratory Testing ... in Hemolytic Anemia ... #Laboratory #Testing ... #workup #diagnosis ... #hematology #hemolysis
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
microangiopathic hemolytic anemia ... a clinical and laboratory ... diagnosis, not ... coagulation and other testing ... #Hematology #Pathology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Tests - AST, ALT, Alkaline ... within liver Alkaline ... Chemistry #Tests #Laboratory ... #Pathophysiology ... #Diagnosis #LFTs
Commonly Observed Laboratory Findings in Hepatic / Liver Failure
 - Elevated conjugated and unconjugated bilirubin -
Commonly Observed Laboratory ... deficiency - Anemia ... leads to chronic anemia ... #Laboratory #Diagnosis ... #Testing
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Most cases diagnosed ... • Pernicious anemia ... collection with EDTA Pathophysiology ... Hyophosphatasia #hepatology ... #diagnosis
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Areas of diagnostic ... decision for repeat testing ... elevation and clinical context ... ALP, alkaline phosphatase ... Abnormal #Algorithm #Hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... Proximal limb muscle wasting ... PBC Labs: • Alkaline ... Differential Diagnosis ... #workup #hepatology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Differential Diagnosis ... especially in the setting ... #differential #diagnosis ... neutrophil #WBC #CBC #hematology ... #pathophysiology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
the presence of anemia ... more time for the laboratory ... (to support a diagnosis ... #workup #diagnosis ... #testing #Rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
and fever) and laboratory ... Differential Diagnosis ... Malignancy (e.g. hematologic ... syndrome in the context ... lymphopenia, low PLT • Anemia