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diagnosis dermatology differential rheumatology systemic disorders hyperpigmentation management pruritus secondary antinxp2 antinxp2dm classification cryoglobulinemia cryoglobulins dermatomyositis erythematosus hypopigmentation lupus primary
Disorders of Pigmentations - Hypopigmentation and Hyperpigmentation - Differential Diagnosis Algorithm HYPOPIGMENTATION Diffuse Congenital - Generalized hypopigmentation of
Diffuse Congenital - Generalized ... of hair, eyes, skin ... Tanning • Adverse cutaneous ... McCune Albright syndrome ... #causes
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Pruritus - Generalized ... Differential Diagnosis Algorithm ... Systemic and Primary Causes ... Myelodisplastic syndrome ... #causes
Skin Hyperpigmentation - Differential Diagnosis Algorithm Diffuse: • Tanning • Adverse cutaneous drug eruption • Addison's disease
Skin Hyperpigmentation ... Tanning • Adverse cutaneous ... McCune Albright syndrome ... #dermatology #Differential ... #causes
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... - Purpura - Skin ... Cryoglobulins Cause ... : • Clinical triad ... Henoch-Schönlein purpura) • Cutaneous
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary Skin ... Myelodisplastic syndrome ... secondary #systemic #generalized ... #dermatology #Differential ... #causes
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... 3rd Decade Skin ... in the context ... Clinical Features ... Seizures • Strokes Skin
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Lacrimal swelling • Skin ... Hypocomplementemia • Can cause ... salivary ducts Clinical ... ) • Cutaneous vasculitis ... Nephrogenic DI Hematologic
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
DM with generalized ... muscle weakness • Generalized ... in the neck Cutaneous ... auricular papules Clinical ... Muscle atrophy may cause
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