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Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Treatment Stop offending agents: • List as allergies
Symptoms (DRESS) Syndrome ... Treatment Stop ... Alternatives: cyclosporine ... BrighamChiefs #DRESS #Syndrome ... #Treatment #Management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... factor (GCSF) treatments ... marrow studies Treatment ... Immunosuppressive treatment ... examples: ATG and cyclosporine
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... marrow-failure syndromes ... aplastic anemia Treatment ... Immunosuppression - cyclosporine
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
disease: symptomatic treatment ... Line Therapy: Cyclosporin ... SinaiBmoreIMRes #DRESS #Syndrome
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
TAFRO TAFRO syndrome ... Organomegaly TAFRO syndrome ... nodes TAFRO syndrome ... Hypoalbuminemia Treatment ... , Tocilizumab, Cyclosporin
Causes of Hyperuricemia Increased production • Solid-organ transplant • Tumor lysis syndrome • Rhabdomyolysis • Lesch Nyhan
• Tumor lysis syndrome ... • Lesch Nyhan syndrome ... nicotinic acid - cyclosporine ... (ciclosporin)-reduced
Hyperthermia Syndromes Comparison Serotonin Syndrome - NMS - Malignant Hyperthermia - Malignant Catatonia Cause - Onset - Vitals
Hyperthermia Syndromes ... Comparison Serotonin Syndrome ... Mental Status - Treatment ... #Hyperthermia #Syndromes
Hirsutism & Virilization - Differential Diagnosis Algorithm ADRENAL EXCESS Ovarian • Polycystic Ovarian Syndrome • Hyperthecosis • Tumor Adrenal
Polycystic Ovarian Syndrome ... • Cushing's Syndrome ... Insulin Resistance Syndrome ... Phenytoin • Cyclosporine ... Paraneoplastic Syndrome
Hypomagnesemia - Differential Diagnosis Renal Causes of Hypomagnesemia - Familial: Bartter syndrome and Gitelman syndrome, Isolated recessive hypomagnesemia,
Familial: Bartter syndrome ... and Gitelman syndrome ... cisplatin, Tacrolimus, cyclosporine
Spinal Cord Injury Syndromes Complete, Incomplete, Paraplegia, Tetraplegia Incomplete Spinal Cord Syndromes: - Brown Sequard Syndrome - Anterior
Spinal Cord Injury Syndromes ... Brown Sequard Syndrome ... Anterior Cord Syndrome ... Posterior Cord Syndrome ... - Central Cord Syndrome
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