9 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin ... of anemia include ... • hemolytic anemia ... sensitize red blood cells ... #hematology #diagnosis
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
- Tamponade Pulmonary ... - Asthma - COPD ... Transverse myelitis • Hematology ... : - Anemia • ... diagnosis #causes #pulmonary
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
nephrocalcinosis • CPPD ... • Pernicious anemia ... mineralization Symptoms ... respiratory failure • Neurologic ... Hyophosphatasia #hepatology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Algorithm • Sickle cells ... Agglutination - Cold ... ARUPLabs #Hemolytic #Anemia ... Algorithm #workup #hematology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Cryofibrinogen is a cold ... - Albumin - Cold ... Cryofibrinogenemia Symptoms ... may include: • Cold ... #hematology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
et diutinum Neurologic ... (-) hemolytic anemia ... due to cold IgG ... Paraproteinemias #Hematology
Evaluation of Recurrent Falls

Core Concept:
Maintaining an upright posture requires the integrated function of multiple systems.
Disruption in
cardiogenic) - Pulmonary ... embolism - Severe anemia ... presyncope, exertional symptoms ... ) - Spinal cord ... Evaluation #Geriatrics #Neurology
Anorexia Nervosa: Complications
CARDIAC ABNORMALITIES
 - Functional: Low BP, Sinus bradycardia, prolonged QT interval
 - Structural: Reduced
/ Hypovolemia NEUROLOGIC ... and memory loss HEMATOLOGIC ... lymphocytosis, mild anemia ... Hypothermia and Cold ... diagnosis #signs #symptoms
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
syndrome): - Hematologic ... replacement Cord ... “big & sticky” cells ... up to 30 %) - Symptoms ... renal failure, pulmonary