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diagnosis differential management causes lfts acute aflp obstetrics pregnancy transaminitis abnormal aclf aih anemia aplastic asterixis autoimmune chemistry chronic cirrhosis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Clinical Guidelines ... Injury (DILI) ... Viral Hepatitis ... #Hepatology #gastroenterology ... #management #diagnosis
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Injury - Differential ... Diagnosis Hepatocellular ... Ascariasis, Choledochal Cyst ... #Acute #algorithm ... #hepatology
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Algorithm Malignant ... Non-Malignant • Fatty Liver ... • Cysts • Hemochromatosis ... • Right Heart Failure ... #Hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
: Liver Injury ... failure 1) Hepatocellular ... #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular ... Ascariasis, Choledochal cyst ... #injury #hepatitis ... #algorithm #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis ... Algorithm DILI ... • Autoimmune hepatitis ... #Injury #Diagnosis ... #Algorithm #hepatology
Flapping tremors of Asterixis DDx - Decompensated cirrhosis or acute liver failure. - Renal failure /azotemia. - Respiratory failure with
cirrhosis or acute liver ... failure ... - Renal failure ... #PhysicalExam #clinical ... #diagnosis #video
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 Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Check Acute viral hepatitis ... Failure (ALF): ... • Liver injury ... #chemistry #diagnosis ... #differential #Hepatology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
disease to acute liver ... failure ... hepatocellular pattern of liver ... injury, though ... #Management #Hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
failure rapidly ... → Multiorgan failure ... ) Differential Diagnosis ... : Viral Hepatitis ... #Pregnancy #hepatology
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