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diagnosis differential management causes gastroenterology hepatitis lfts transaminitis aclf aflp aih aki autoimmune chemistry choosingwisely chronic cirrhosis drug druginduced ebm
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Injury (DILI) ... #differential #Diagnosis ... gastroenterology #algorithm ... gastroenterology #hepatology
Focused evaluation algorithm for acute liver injury #Liver #Injury #Acute #Evaluation #Algorithm #Diagnosis #Hepatology
for acute liver ... injury #Liver ... #Injury #Acute ... #Evaluation #Algorithm ... #Diagnosis #Hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... Algorithm DILI ... dechallenge • Acute ... #Injury #Diagnosis ... #Algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential Diagnosis ... Algorithm Vascular ... Ascariasis, Choledochal cyst ... #algorithm #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
- Differential Diagnosis ... Hepatopathy • Acute ... (>1000): • DILI ... injury) • Ischemic ... #hepatology #transaminitis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... ACLF) Clinical Guidelines ... Injury (DILI) ... Failure #Cirrhosis #Hepatology ... gastroenterology #management #diagnosis
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Diagnosis Hepatocellular ... Ascariasis, Choledochal Cyst ... #Acute #algorithm ... #hepatology
Shotgun Laboratory Testing for Severe Acute Livery Injury https://www.journalofhospitalmedicine.com/jhospmed/article/143598/hospital-medicine/ammonia-levels-and-hepatic-encephalopathy-patients-known #TWDFNR #Testing #Laboratory #LiverInjury #Diagnosis #Workup #Hepatology #EBM #ChoosingWisely
Testing for Severe Acute ... Livery Injury ... #LiverInjury #Diagnosis ... #Workup #Hepatology
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 Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
injury < 26 weeks ... Unconjugated Bili ... > 90% of Total Bili ... #chemistry #diagnosis ... #differential #Hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... headache, malaise) → Acute ... 10x ULN), ↑Tbili/Dbili ... ) Differential Diagnosis ... #Pregnancy #hepatology
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