11 results
Lactic Acidosis Classification - Type A vs Type B
Type A Lactic Acidosis: Sepsis, Ischemic bowel, Hemorrhagic
Lactic Acidosis ... Acidosis: Liver ... Short bowel (D-lactate ... #TypeA #TypeB #diagnosis ... #differential #
High Anion Gap Metabolic Acidosis (HAGMA) - Differential Diagnosis - GOLDMARK

Glycols - ethylene and propylene glycol
Oxoproline
Acidosis (HAGMA ... ) - Differential ... Diagnosis - GOLDMARK ... toxicity causes lactic ... #Differential #
Lactic Acidosis - Differential Diagnosis Framework

Type A: Impaired O2 Delivery (DO2)
 • Decreased O2 Delivery: Hypotension
Lactic Acidosis ... - Differential Diagnosis ... Clearance: Systemic liver ... Inborn Errors of Metabolism ... #Acidosis #Differential
Lactic Acidosis - Classification and Differential Diagnosis
Type A Lactic Acidosis: Inadequate Oxygen Delivery
 • Anaerobic muscular
Lactic Acidosis ... Diagnosis Type ... A Lactic Acidosis ... inborn errors of metabolism ... #Differential #
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Metformin Associated Lactic ... Acidosis (MALA) ... cycle found in the liver ... Diagnosis of MALA ... acidosis including
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Acidosis - Differential ... impairment of cellular metabolism ... sweat) - its metabolism ... #Lactic #Acidosis ... #Elevation #Differential
Type B Lactic Acidosis
Elevated lactic acid when no systemic hypoperfusion is apparent
Causes:
 • Drugs (metformin, linezolid,
Type B Lactic Acidosis ... agonist activity • Liver ... to clear) • D-lactate ... #differential # ... diagnosis
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
Thiamine Deficiency - Differential ... Diagnosis Framework ... also seen • Lactic ... acidosis may not ... GFR • Acute liver
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Heat Stroke - Differential ... Diagnosis Framework ... • Labs: - Metabolic ... Possible DIC - Mild lactic ... acidosis - CPK
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
stores in the liver ... But we also have Lactic ... The metabolism of ... convert Pyruvate to Lactate ... #diagnosis #differential