5152 results
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
in inflammatory cytokines ... → Inflammation causes ... endpoint of all-cause ... heartfailure #diagnosis #management
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
Endotoxins, Toxins, Cytokines ... rapidly fatal • Causes ... Identify underlying cause ... Cooling blankets can cause ... comparison #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
pro-inflammatory cytokines ... Drugs, Unknown cause ... 100 mg/m2) : in case ... emergency, ICU in case ... Lymphohistiocytosis #diagnosis #management
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... countries (11-24 cases ... Epithelioid cells → cytokines ... symptoms are not caused ... Sarcoidosis #Diagnosis #Management
Hypothermia in Sepsis - Pathophysiology
 • 20% of septic pts → HYPOTHERMIA
 • Increased mortality 62%
proinflammatory cytokines ... anti-inflammatory cytokine
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
accumulated inflammatory cytokines ... Causes purpura & ... TRALI): Leading cause ... more likely to cause ... Transfusion #diagnosis #management
Eosinophils (Eos) and hypereosinophilia (HE)
Caused by eosinophilopoietic cytokines
Common causes:
 - Drug reaction
 - Helminth infection
 -
hypereosinophilia (HE) Caused ... eosinophilopoietic cytokines ... Common causes: ... disease Rare causes ... Differential #Diagnosis #Causes
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
accumulated inflammatory cytokines ... Causes purpura & ... TRALI): Leading cause ... more likely to cause ... Transfusions #diagnosis #management
Drugs Causing Acute Pancreatitis

Class Ia: The medications in which there was a rechallenge and other causes
rechallenge and other causes ... out other common causes ... Class II: Cases ... and atleast4 case ... #Pancreatitis #Causes
A quick infographic on various pearls about atopic dermatitis, a disease with an increasing burden on
risk factors, management ... skin barrier, cytokines ... #management #medications ... treatment #diagnosis #causes