2076 results
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
Immune Reactions ... Inhibition of cytokine ... Inhibition of cytokine
Algorithm for the Evaluation and Management of Transfusion Reactions

This algorithm was developed by Dr. Eric Madden,
Algorithm for the ... of Transfusion Reactions ... This algorithm ... #Transfusion #Reactions ... #Algorithm #Diagnosis
Hypothermia in Sepsis - Pathophysiology
 • 20% of septic pts → HYPOTHERMIA
 • Increased mortality 62%
proinflammatory cytokines ... anti-inflammatory cytokine
Eosinophils (Eos) and hypereosinophilia (HE)
Caused by eosinophilopoietic cytokines
Common causes:
 - Drug reaction
 - Helminth infection
 -
eosinophilopoietic cytokines ... causes: - Drug reaction ... infection - Allergic reaction
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
hypersensitivity reactions ... Acute transfusion reaction ... release inflammatory cytokines ... hypersensitivity #reactions
Differential Diagnosis of Leukemoid Reaction

Retrospective review of 135 patients with WBC >25k:
 - 48% infection
 -
Diagnosis of Leukemoid Reaction ... #Leukemoid #Reaction ... #Leukocytosis #Algorithm
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... syndrome, POEMS • Reaction ... Exercise, Allergic reactions ... Differential #Diagnosis #Algorithm
Estimated Incidence of Transfusion Reactions
Graphical Depiction of transfusion reactions ordered from most highest to lowest incidence.
#Diagnosis
of Transfusion Reactions ... of transfusion reactions ... Transfusion #Consent #Reactions
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Penicillin-induced drug reaction ... Dermatitis (ie. reaction ... Allergy #Allergic #Reactions
Anaphylaxis: Pathogenesis
Anaphylaxis is a Type 1 hypersensitivity reaction
While the primary mechanism of anaphylaxis is mast cell
hypersensitivity reaction ... mediators (e.g. cytokines