2959 results
Eosinophils (Eos) and hypereosinophilia (HE)
Caused by eosinophilopoietic cytokines
Common causes:
 - Drug reaction
 - Helminth infection
 -
eosinophilopoietic cytokines ... Common causes: ... - Drug reaction ... infection - Allergic reaction ... disease Rare causes
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
hypersensitivity reactions ... Allergen-specific lgE causes ... Acute transfusion reaction ... release inflammatory cytokines ... hypersensitivity #reactions
Kounis Syndrome

Acute coronary syndrome (symptoms such as chest pain relating to reduced blood flow to the
to the heart) caused ... by an allergic reaction ... strong immune reaction ... of inflammatory cytokines ... agents from the reaction
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion Reactions ... accumulated inflammatory cytokines ... Causes purpura & ... TRALI): Leading cause ... more likely to cause
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
common immune reaction ... accumulated inflammatory cytokines ... Causes purpura & ... TRALI): Leading cause ... more likely to cause
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
Immune Reactions ... Inhibition of cytokine ... Inhibition of cytokine
Hypothermia in Sepsis - Pathophysiology
 • 20% of septic pts → HYPOTHERMIA
 • Increased mortality 62%
proinflammatory cytokines ... anti-inflammatory cytokine
Fracture Healing (and disruptors of this process)
Inflammatory Stage (0-7d)
 • Fracture disrupts local blood vessels ->
> Inflammatory reaction ... & release of cytokines ... Fluoroquinolones - Causes
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
during an allergic reaction ... Or Inflammatory Reactions ... Chickenpox Other Causes ... Differential #Diagnosis #causes
Hemolysis Classification - Intrinsic and Extrinsic Causes

Commentary: Another way to think of immune hemolysis would be
and Extrinsic Causes ... autoimmune (most of the causes ... hemolytic transfusion reactions ... Differential #Diagnosis #Causes