145 results
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
Immune Reactions ... Inhibition of cytokine ... Inhibition of cytokine
Myelopathy - Injury to the entire spinal cord - Signs and Symptoms
 • Ataxia (early sign)
spinal cord - Signs ... Ataxia (early sign ... weakness (late sign ... dexterity loss (early signs ... #symptoms #msk
Eosinophils (Eos) and hypereosinophilia (HE)
Caused by eosinophilopoietic cytokines
Common causes:
 - Drug reaction
 - Helminth infection
 -
eosinophilopoietic cytokines ... causes: - Drug reaction ... infection - Allergic reaction
Cubital Tunnel Syndrome: Pathogenesis and clinical findings

 • Paresthesia of 5th and medial half of 4th
test • + Tinel sign ... • + Froment's sign ... + Wartenbergs sign ... pathophysiology #signs ... #symptoms #msk
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
hypersensitivity reactions ... Acute transfusion reaction ... release inflammatory cytokines ... hypersensitivity #reactions
Flexor Tenosynovitis (FTS)

The clinical diagnosis of FTS is made using Kanavel’s Signs:
 - Fusiform swelling.
 -
using Kanavel’s Signs ... Kanavels #Criteria #Sign ... #Hand #MSK #Diagnosis
Radiculopathy: Signs and Symptoms
 • Back/Neck Pain
 • Decr Range of motion
 • Abnormal posturing
 •
Radiculopathy: Signs ... • Spurling's sign ... pain Lasegue's sign ... Radiculopathy #MSK ... #diagnosis #signs
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS
represents
Drug Reaction with ... Eosinophilia and Systemic Signs ... hypersensitivity reaction ... with allergic reaction
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS
represents
Drug Reaction with ... Eosinophilia and Systemic Signs ... hypersensitivity reaction ... with allergic reaction
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
alter inflammatory cytokine ... yrs old; F>M Signs ... Pathophysiology #Diagnosis #Signs