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diagnosis rheumatology differential oncology allergy anemia aplastic cardiology classification common cryofibrinogenemia cryoglobulinemia cryoglobulins cvid dermatology endocarditis hypogammaglobulinemia immunodeficiency immunology infectiousdiseases
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... : HCV infection, ... DDX: • ANCA (Antineutrophil ... classification #rheumatology
Approach to Elevated Tryptase - Differential Diagnosis Framework The DDx of elevated tryptase can be broken down
Framework The DDx ... • Parasitic infections ... • Mast cell activation ... syndrome • Mastocytosis ... • Other hematologic
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... kidney failure DDX ... SLE], AOSD) • Infection ... MAS #Macrophage #Activation ... #Management #Hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Causes: - Idiopathic ... , breast CA - Hematologic ... gastrointestinal infection ... DDX: - Pyoderma ... Leukocytoclastic vasculitis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... Idiopathic • Infections ... and thymoma DDX ... Anemia #oncology #hematology ... #diagnosis #management
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
malignancies, vasculitis ... Malignancy • Infections ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... #hematology
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
Hypercoagulable (APLAS) Microbiology ... Glomerulonephritis DDX ... valvular disease • Vasculitis ... Cholesterol emboli syndrome ... Septic emboli cause
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
40 years old DDX ... ANCA-associated vasculitis ... - Infectious disorders ... TAFRO #diagnosis #management ... #rheumatology #
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
dysfunction DDX ... Behcet disease • Infections ... Bacterial ○ Viral infection ... Polychondritis #rheumatology ... #diagnosis #management
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