12 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... procedures - Infection ... IgA, IgG, IgM (CVID ... not required in all ... #Workup #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
weeks without infection ... lymphoproliferative disorders ... lymphocyte > 5000/microL ... Leukemia #diagnosis #workup ... #oncology #hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency (CVID ... disorder with hypogammaglobulinemia ... to impaired B-cell ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... - Trauma - Infection ... Vasculitis - Collagen disorders ... RA, Sjogren's, GPA ... deficiency Work
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... associated vasculitis - GPA ... diagnosis #types #classification ... #rheumatology #
Approach to Elevated Tryptase - Differential Diagnosis Framework

The DDx of elevated tryptase can be broken down
Framework The DDx ... Eosinophilic GI Disorders ... • Parasitic infections ... : • Mast cell ... Differential #Diagnosis #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... Include: • Viral infections ... Connective tissue disorders ... gastric tumors • Hematology ... differential #diagnosis #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... • Parvovirus infection ... Workup: • Complete ... Syndromes #diagnosis #hematology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Rare Disorder: ... sudden onset of a rash ... - Rash: multiple ... Causes: - Idiopathic ... , breast CA - Hematologic
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
cryoglobulinemia Associated Disorders ... Malignancy • Infections ... disease 2019 (COVID ... cryoglobulins • Negative causes ... #hematology