11 results
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Maculopapular rash ... arteritis Infections ... (inflamed blood ... #rash #diagnosis
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... - Vasculitis ... : • Complete blood ... • Fecal occult blood ... cryoglobulins • Skin
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
weeks without infection ... Hepatomegaly • Skin ... Lymphocytosis: Absolute blood ... lymphocyte > 5000/microL ... workup #oncology #hematology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
- Rash: multiple ... Causes: - Idiopathic ... , breast CA - Hematologic ... Leukocytoclastic vasculitis ... neutrophils in the blood
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... mucositis - Rash ... to exclude are infections ... pulses, bruis, or blood ... Large Vessel: Blood
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
to exclude are infections ... pulses, bruits, or blood ... CRP GCA (Giant Cell ... , mucositis • Rash ... tract, and often causes
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... petechiae) • Frequent infections ... Macrocytic anemia DDX ... • Parvovirus infection ... Syndromes #diagnosis #hematology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
which can plug blood ... malignancies, vasculitis ... Malignancy • Infections ... cryoglobulins • Negative causes ... #hematology
Acute Generalized Exanthematous Pustulosis (AGEP)

AGEP is largely a clinical diagnosis based on classical skin findings in
based on classical skin ... or had a recent infection ... Causes? ... - diltiazem Infections ... Elevated white blood
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
Microbiology: Blood ... valvular disease • Vasculitis ... Septic emboli cause ... Differential #Diagnosis #cardiology ... #infectiousdiseases