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Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Liver Injury (DILI ... ) DILI Types: ... • Cholestatic DILI ... Idiosyncratic #differential ... gastroenterology #algorithm
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Liver Injury - Differential ... Diagnosis Algorithm ... • Iatrogenic: DILI ... injury #hepatitis #differential ... #diagnosis #algorithm
Drugs and Classes Associated with DILI and Type of Liver Injury #Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
Associated with DILI ... #Medications #Differential ... Pharmacology #Causes #DILI
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 Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Liver Injury (DILI ... Stepwise Diagnosis Algorithm ... DILI suspicion ... injury, Previous DILI ... Injury #Diagnosis #Algorithm
Amiodarone-Induced Lung Iniurv (AILI) - Timeline Hours to days (peri-procedurally): ARDS Days to months: DAH Weeks: Eosinophilic pneumonia Weeks to
Amiodarone-Induced Lung Iniurv (AILI ... Induced #LungIniurv #AILI ... pulmonary #diagnosis #differential
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
Transaminitis - Differential ... • Iatrogenic: DILI ... Transaminases #hepatitis #Differential
Algorithmic Approach and Differential Diagnosis - Hypercalcemia #Diagnosis #Hypercalcemia #Differential #Algorithm #Workup
Algorithmic Approach ... and Differential ... Hypercalcemia #Differential ... #Algorithm #Workup
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 Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - Differential ... (>1000): • DILI ... #Tests #LFTs #Differential
Drug-Induced Liver Injury - Pathophysiology Indirect Idiosyncratic Direct BWH Medicine Chiefs @BrighamChiefs #DILI #DrugInduced #Liver #Injury #Pathophysiology #hepatology
BrighamChiefs #DILI
Algorithmic Approach to Peripheral Cyanosis #Peripheral #Cyanosis #Diagnosis #Algorithm #Differential
Algorithmic Approach ... Cyanosis #Diagnosis #Algorithm ... #Differential
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