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Differential diagnosis on HRCT
Most of our knowledge about imaging findings in interstitial lung disease comes from
Differential diagnosis ... about imaging findings ... low attenuation (table ... in many cases UIP ... #Pulmonary #CXR
The idiopathic interstitial pneumonias (IIPs) comprise a heterogenous group of disorders. 
They represent fundamental responses of
listed in the table ... on HRCT and histology ... #Diagnosis #Radiology ... #Pulmonary #CTChest ... IdiopathicInterstitialPneumonia #ILD
Upper lung zone preference is seen in:
- Inhaled particles: pneumoconiosis (silica or coal)
- Smoking related diseases
bronchiolitis (RB-ILD ... is seen in: - UIP ... edema #Diagnosis ... #HRCT #ChestCT ... #Differential #Table
The fourth pattern includes abnormalities that result in decreased lung attenuation or air-filled lesions.
These include:
- Emphysema
-
Lung cysts (LAM, LIP ... on the basis of HRCT ... findings. ... #Diagnosis #Radiology ... #Pulmonary #CTChest
Figure 3 HRCT-LUS correlation in normal lung, pulmonary congestion, rheumatoid lung disease, idiopathic pulmonary fibrosis.
Notes: (A)
Figure 3 HRCT-LUS ... artifact); (G) UIP ... #Clinical #Diagnosis ... #Correlation #Table ... #ILD #Findings
UIP with honeycombing (left) and chronic HP (right)
Differential diagnosis of Hypersensitivity Pneumonitis.
Subacute stage:
- RB-ILD: seen in
) Differential diagnosis ... Subacute stage: - RB-ILD ... show very similar HRCT ... findings ... #Radiology #CTChest
UIP
UIP is a histologic pattern of pulmonary fibrosis.
On a chest X-ray UIP manifests as a reticular
pattern of pulmonary ... On a chest X-ray ... A HRCT is needed ... to confirm the diagnosis ... HRCT demonstrated
Acute interstitial pneumonia (AIP, earlier named Hamman Rich Pneumonitis) is a rare idiopathic lung disease characterized
aswell as the HRCT ... findings in AIP ... suggestive of the diagnosis ... Clinical #Radiology #CTChest ... #ILD #RadiologyAssistant
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... rapidly develops (DIC ... Multiorgan failure Findings ... AP, ↑INR, ↑BUN/Cr ... ↓Antithrombin Ill
Basic Interpretation
A structured approach to interpretation of HRCT involves the following questions:
What is the dominant HR-pattern:
reticular
nodular
high
there additional findings ... bronchiectasis) #Diagnosis ... #Radiology #Pulmonary ... #HRCT #CTChest ... Interpretation #Algorithm #ILD