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Diffuse large B cell lymphoma (DLBCL) - Management and Treatment Algorithm

By Matthew Ho, MD PhD @MatthewHoMD

#Diffuse
Diffuse large B cell ... lymphoma (DLBCL ... Diffuse #large #Bcell ... #lymphoma #DLBCL
Lymphoma Classification
Non-Hodgkin - T-Cell Lymphoma
Non-Hodgkin - B-Cell Lymphomas:
 • Highly Aggressive - Burkitt, Aggresive
 • Aggressive
Non-Hodgkin - T-Cell ... Non-Hodgkin - B-Cell ... • Aggressive - DLBCL ... , Mantle Cell
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
lymphocytes/Mature B cell ... disease • B cell ... CLL and other C Cell ... AIHA • Pure red cell ... : Transform to DLBCL
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
++: Hodgkin, T-cell ... lymphoma, B-cell ... lymphoma (DLBCL
Continuous B-cell depletion in frequently relapsing, steroid-dependent and steroid-resistant nephrotic syndrome 

Clinical Kidney Journal, , sfy067,
Continuous B-cell ... : Continuous B-cell ... nephondemand #BCell
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases

Acanthocyte (spur cell),  
Basophilic stippling, 
Bite cell,
Pathologic Red Blood Cell ... Acanthocyte (spur cell ... stippling, Bite cell ... , Sickle cell, ... , Target cell
Inflammatory Cascade: Pathogenesis and Clinical Findings
Continued Innate Immunity
 • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
• Humoral: (B cell ... complement system • Cell-mediated ... : (T cell response ... Increased helper cell ... and cytotoxic cell
Causes of Ovarian Mass - Differential Diagnosis Algorithm
Hyperplastic:
 • Polycystic ovary
 • Endometrioid cyst
Functional:
 • Follicular
cystadenoma Germ Cell ... • Granulosa cell ... Germ Cell Malignant ... • Granulosa cell ... tumor • Sertoli Cell
Summary of haemotology cell lineages and the malignancies associated with them. Visit gramproject.com for more medical
of haemotology cell ... hematology #physiology #cell
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... Bite Cell RBC: G6PD ... disease Target Cell ... Artifact Sickle Cell ... SC disease Red Cell