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Diffuse large B cell lymphoma (DLBCL) - Management and Treatment Algorithm

By Matthew Ho, MD PhD @MatthewHoMD

#Diffuse
Diffuse large B ... cell lymphoma (DLBCL ... and Treatment Algorithm ... #Bcell #lymphoma ... #DLBCL #Management
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
lymphocytes/Mature B cell ... accumulate in large ... disease • B cell ... and other C Cell ... : Transform to DLBCL
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Malignancy, 1° PBC ... , 1° PSC, Cystic ... Disease, Sickle Cell ... Causes #Acute #algorithm
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Differential Diagnosis Algorithm ... breast CA, small cell ... , Sickle cell, GVHD ... intestines, white blood cells ... differential #diagnosis #algorithm
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Differential Diagnosis Algorithm ... • Sickle cell ... Cold AIHA • PCH ... Differential #Diagnosis #Algorithm
Diagnostic approach to the admitted patient with possible COVID-19

Initial evaluation
- Chest X-ray
- Lung ultrasound (thorough "lawn-mower"
Nasopharyngeal PCR ... with differential cell ... iBookCC #COVID19 #algorithm
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Angioimmunoblastic T-cell ... the small and large ... Antiribosomal P, APLA, PAC ... : • Chronic B-cell
Langerhans Cell Histiocytosis (LCH)

Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
Langerhans Cell ... type of dendritic cell ... Immunophenotyping: • Large ... Birbeck granules (EM ... LCH #Langerhans #Cell
Common Malignancies That Cause Ascites
The most common malignancies causing ascites are ovarian cancer, pancreatic cancer, gastric
presents with large-volume ... - Signet ring cell ... Hepatocellular Carcinoma – HCC ... CARCINOMATOSIS - Tumor cells ... metastases or HCC