11 results
NOAC / DOAC Pharmacology and Prescribing Cheat Sheet
Novel (or Direct) Oral Anti-Coagulants
 • Rivaroxaban
 • Apixaban
NOAC / DOAC Pharmacology ... Anti-Coagulants • Rivaroxaban ... • Apixaban • Dabigatran ... #NOAC #DOAC #Pharmacology ... AntiCoagulant
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... Clotmaster #VTE #DOAC ... #Oral #Anticoagulant ... #Anticoagulation ... #Dabigatran #Apixaban
Oral Anticoagulation Management Cheat Sheet: Warfarin, Apixaban, Dabigatran, Rivaroxaban
 - Mechanism of Action
 - Routine Blood
Oral Anticoagulation ... Warfarin, Apixaban, Dabigatran ... , Rivaroxaban ... #Anticoagulant ... #DOAC #Management
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
Anticoagulant Agents ... Hepatic, 25% Renal Dabigatran ... Hepatic, 35% Renal #DOAC ... #NOAC #Metabolism ... #anticoagulation
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
accelerates the bridging ... : A new oral anticoagulant ... Heparins #LMWH #UFH #DOAC ... #Dabigatran #Apixaban ... #NOAC #Mechanism
Anticoagulant specific factor inhibition. 

#anticoagulation #clotting #INR #heparin #LMWH #NOAC #warfarin #coumadin #rivaroxaban  #Xarelto #apixaban
Anticoagulant specific ... #anticoagulation ... heparin #LMWH #NOAC ... warfarin #coumadin #rivaroxaban ... #Pradaxa #management
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... not available #DOAC ... #Reversal #NOAC ... #Oral #anticoagulant ... #hematology #management
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
Perioperative Management ... direct acting oral ... determine timing of DOAC ... of Therapy • Dabigatran ... postoperative #DOAC
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
, edoxaban and rivaroxaban ... filtration rate; DOAC ... #DOAC #VTE #Malignancy ... #Anticoagulation ... #Management #Hematology
Effect of Direct Oral Anticoagulants on Hemostatic Tests
Horizontal bars correspond to the approximate range of detectability
Effect of Direct Oral ... Anticoagulants ... concentrations of dabigatran ... thrombin time #doac ... #noac #anticoagulation