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pharmacology noac reversal aptt atrial diagnosis dosing dvt fibrillation loading perioperative preop testing toxicology treatment vte
Oral anticoagulant dosing and bridging for VTE - Dr. Joseph Shatzel @Clotmaster #VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... #Oral #Anticoagulant ... #Anticoagulation ... #Dabigatran #Apixaban ... #Rivaroxaban #Edoxaban
Anticoagulants Common Reversal Agents - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra) - Heparin/LMWH
Anticoagulants Common ... Agents - Warfarin (Coumadin ... (Praxbind) - Apixaban ... (Lixiana), Rivaroxaban ... #hematology #reversal
DOAC Reversal Emergency surgery or urgent procedure Stop anticoagulant treatment; volume resuscitation and transfusion as needed Antidotes: • Apixaban,
Antidotes: • Apixaban ... , Edoxaban or Rivaroxaban ... modified factor Xa • Dabigatran ... #Oral #anticoagulant ... #hematology #management
Effect of Direct Oral Anticoagulants on Hemostatic Tests Horizontal bars correspond to the approximate range of detectability
Effect of Direct Oral ... Anticoagulants ... , rixaroxaban, apixaban ... #noac #anticoagulation ... #hematology #laboratory
Perioperative Management of DOACs Problem: ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
Perioperative Management ... direct acting oral ... of Therapy • Dabigatran ... inhibitor) • Apixaban ... , Edoxaban, Rivaroxaban
Atrial Fibrillation (A-Fib) Summary Symptoms: • Palpitations, light-headedness, dizziness, dyspnea, exercise intolerance, chest pain, near-syncope, syncope. Why? Cardiac: • Valvular heart
typically needed • DOACs ... Xa inhibitors (rivaroxaban ... , apixaban, edoxaban ... #diagnosis #management ... #cardiology
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