14 results
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Clotmaster #VTE #DOAC ... Anticoagulant #Anticoagulation ... #Dabigatran #Apixaban ... #Rivaroxaban #Edoxaban ... #Loading #DVT #Pharmacology
DOAC Cheat Sheet
 • Apixaban, Dabigatran, Edoxaban, Rivaroxaban
 • Renal Dosing
 • Common Drug interactions
 •
Apixaban, Dabigatran ... , Edoxaban, Rivaroxaban ... #anticoagulation ... #CheatSheet #dosing ... #ckd #pharmacology
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
AFib: CrCl 15-50 ... #CheatSheet #Dosing ... #Hematology #Pharmacology ... #Apixaban #Rivaroxaban ... #Dabigatran #Edoxaban
Switching Between Anticoagulants and DOACs
VKA, Dabigatran, Rivaroxaban, Apixaban, Edoxaban, Betrixaban, DOAC, Parenteral anticoagulant

DOI: 10.1161/JAHA.120.017559

#Anticoagulants #DOACs #anticoagulation
VKA, Dabigatran ... , Rivaroxaban, Apixaban ... , Edoxaban, Betrixaban ... #anticoagulation ... Switching #hematology #pharmacology
Oral Anticoagulation Management Cheat Sheet: Warfarin, Apixaban, Dabigatran, Rivaroxaban
 - Mechanism of Action
 - Routine Blood
Sheet: Warfarin, Apixaban ... , Dabigatran, Rivaroxaban ... Anticoagulant #DOAC ... #Pharmacology # ... Stop #Perioperative
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Protamine sulfate - Dabigatran ... (Praxbind) - Apixaban ... Betrixaban (Bevyxxa), Edoxaban ... (Lixiana), Rivaroxaban ... #doac #noac #pharmacology
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
Hepatic, 0% Renal Apixaban ... Hepatic, 25% Renal Dabigatran ... Hepatic, 80% Renal Edoxaban ... Hepatic, 50% Renal Rivaroxaban ... #Pharmacology #
Anticoagulant specific factor inhibition. 

#anticoagulation #clotting #INR #heparin #LMWH #NOAC #warfarin #coumadin #rivaroxaban  #Xarelto #apixaban
#anticoagulation ... #Xarelto #apixaban ... #Eliquis #dabigatran ... #Pradaxa #management ... #pharmacology #
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
Perioperative Management ... of Therapy • Dabigatran ... inhibitor) • Apixaban ... , Edoxaban, Rivaroxaban ... #pharmacology #
Warfarin to DOAC and DOAC to Warfarin Transitions 

Here are a couple of charts to help
Quick tip: apixaban ... and dabigatran ... Rivaroxaban is < ... Edoxaban is <2.5 ... #Pharmacology #