9 results
Anticoagulant specific factor inhibition. 

#anticoagulation #clotting #INR #heparin #LMWH #NOAC #warfarin #coumadin #rivaroxaban  #Xarelto #apixaban
Anticoagulant specific ... #anticoagulation ... #clotting #INR ... heparin #LMWH #NOAC ... #rivaroxaban #
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... Clotmaster #VTE #DOAC ... #Oral #Anticoagulant ... #Anticoagulation ... #Hematology
Oral Anticoagulation Management Cheat Sheet: Warfarin, Apixaban, Dabigatran, Rivaroxaban
 - Mechanism of Action
 - Routine Blood
Sheet: Warfarin ... , Apixaban, Dabigatran ... , Rivaroxaban ... #Anticoagulant ... #DOAC #Management
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Anticoagulants Common ... Reversal Agents - Warfarin ... Protamine sulfate - Dabigatran ... #doac #noac #pharmacology ... #hematology #reversal
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
and Novel Oral Anticoagulants ... or a new oral anticoagulant ... #Pharmacology #Pathophysiology ... Heparins #LMWH #UFH #DOAC ... #NOAC #Mechanism
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
anticoagulant treatment ... not available #DOAC ... #Reversal #NOAC ... #Oral #anticoagulant ... #hematology #management
Anticoagulant Bridging

 • Switching from LMWH
 • Switching from UFH
 • Switching from DOAC to Warfarin
Anticoagulant Bridging ... to DOAC (No Bridging ... Kfischer_10 #Anticoagulant ... #Bridging #anticoagulation ... management #hematology
Effect of Direct Oral Anticoagulants on Hemostatic Tests
Horizontal bars correspond to the approximate range of detectability
of Direct Oral Anticoagulants ... ; ECT = ecarin clotting ... thrombin time #doac ... #noac #anticoagulation ... #testing #aptt
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
For patients on warfarin ... direct acting oral anticoagulants ... to assess for anticoagulant ... determine timing of DOAC ... postoperative #DOAC