9 results
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
dosing and bridging ... Clotmaster #VTE #DOAC ... #Bridging #Dosing ... #Anticoagulation ... #Hematology
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Anticoagulants Common ... Reversal Agents - Warfarin ... Protamine sulfate - Dabigatran ... #doac #noac #pharmacology ... #hematology #reversal
Anticoagulant specific factor inhibition. 

#anticoagulation #clotting #INR #heparin #LMWH #NOAC #warfarin #coumadin #rivaroxaban  #Xarelto #apixaban
Anticoagulant specific ... #anticoagulation ... heparin #LMWH #NOAC ... #rivaroxaban # ... #pharmacology #
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
DOAC: Cheat Sheet ... AFib: CrCl 15-50 ... @Bloodman #DOAC ... #Hematology #Pharmacology ... #NOAC
Oral Anticoagulation Management Cheat Sheet: Warfarin, Apixaban, Dabigatran, Rivaroxaban
 - Mechanism of Action
 - Routine Blood
Sheet: Warfarin ... , Apixaban, Dabigatran ... , Rivaroxaban ... #Anticoagulant ... #DOAC #Management
Anticoagulant Bridging

 • Switching from LMWH
 • Switching from UFH
 • Switching from DOAC to Warfarin
Anticoagulant Bridging ... Switching from DOAC ... to DOAC (No Bridging ... #Bridging #anticoagulation ... management #hematology
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
(e.g. warfarin) ... accelerates the bridging ... Heparins #LMWH #UFH #DOAC ... #Dabigatran #Apixaban ... #NOAC #Mechanism
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
For patients on warfarin ... determine timing of DOAC ... of Therapy • Dabigatran ... postoperative #DOAC ... #Treatment #pharmacology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
platelet #thrombin #clot ... #models #hematology ... pathophysiology #anticoagulation ... #anticoagulant ... #Warfarin #Dabigatran