12 results
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... Clotmaster #VTE #DOAC ... #Oral #Anticoagulant ... #Anticoagulation ... #Rivaroxaban #Edoxaban
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
Anticoagulant Agents ... Warfarin - 100% ... Hepatic, 35% Renal #DOAC ... #NOAC #Metabolism ... #Pharmacology #
Oral Anticoagulation Management Cheat Sheet: Warfarin, Apixaban, Dabigatran, Rivaroxaban
 - Mechanism of Action
 - Routine Blood
Oral Anticoagulation ... Sheet: Warfarin ... , Rivaroxaban ... #Anticoagulant ... #DOAC #Management
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Anticoagulants Common ... Reversal Agents - Warfarin ... Protamine sulfate - Dabigatran ... (Lixiana), Rivaroxaban ... #doac #noac #pharmacology
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
Anticoagulants ... anticoagulants ... : A new oral anticoagulant ... Heparins #LMWH #UFH #DOAC ... #NOAC #Mechanism
Anticoagulant specific factor inhibition. 

#anticoagulation #clotting #INR #heparin #LMWH #NOAC #warfarin #coumadin #rivaroxaban  #Xarelto #apixaban
Anticoagulant specific ... #anticoagulation ... #clotting #INR ... heparin #LMWH #NOAC ... #rivaroxaban #
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... procedure Stop anticoagulant ... not available #DOAC ... #Reversal #NOAC ... #Oral #anticoagulant
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
Perioperative Management ... anticoagulants ... to assess for anticoagulant ... determine timing of DOAC ... postoperative #DOAC
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
and rivaroxaban ... anticoagulants ... filtration rate; DOAC ... anticoagulant; ... #DOAC #VTE #Malignancy
Effect of Direct Oral Anticoagulants on Hemostatic Tests
Horizontal bars correspond to the approximate range of detectability
Effect of Direct Oral ... Anticoagulants ... and edoxaban. ... thrombin time #doac ... #noac #anticoagulation