5 results
Oral Anticoagulation Management Cheat Sheet: Warfarin, Apixaban, Dabigatran, Rivaroxaban
 - Mechanism of Action
 - Routine Blood
Oral Anticoagulation ... Sheet: Warfarin ... , Rivaroxaban ... #DOAC #Management ... #Stop #Perioperative
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
of Oral Anticoagulant ... Agents Warfarin ... Hepatic, 35% Renal #DOAC ... #NOAC #Metabolism ... Clearance #oral
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... urgent procedure Stop ... not available #DOAC ... #Reversal #NOAC ... #Oral #anticoagulant
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
Perioperative Management ... direct acting oral ... determine timing of DOAC ... postoperative #DOAC ... #pharmacology #
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
e.g. warfarin) for ... : A new oral anticoagulant ... Heparins #LMWH #UFH #DOAC ... #Dabigatran #Apixaban ... #NOAC #Mechanism