8 results
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... #DOAC #Bridging ... Anticoagulant #Anticoagulation ... #Dabigatran #Apixaban ... #Rivaroxaban #Edoxaban
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
- Atrial Fibrillation ... AFib: CrCl 15-50 ... OralAnticoagulant #Anticoagulation ... #Hematology #Pharmacology ... #Apixaban #Rivaroxaban
Oral Anticoagulation Management Cheat Sheet: Warfarin, Apixaban, Dabigatran, Rivaroxaban
 - Mechanism of Action
 - Routine Blood
Oral Anticoagulation ... Sheet: Warfarin, Apixaban ... , Dabigatran, Rivaroxaban ... #Anticoagulant ... #DOAC #Management
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
Anticoagulant Agents ... Hepatic, 0% Renal Apixaban ... Hepatic, 25% Renal Dabigatran ... #Pharmacology # ... #anticoagulation
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
the mainstay of VTE ... accelerates the bridging ... : A new oral anticoagulant ... Heparins #LMWH #UFH #DOAC ... #Dabigatran #Apixaban
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
, edoxaban and rivaroxaban ... anticoagulants ... controlled trial ... #DOAC #VTE #Malignancy ... #Anticoagulation
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
direct acting oral ... of Therapy • Dabigatran ... inhibitor) • Apixaban ... , Edoxaban, Rivaroxaban ... Management #Treatment #pharmacology
Atrial Fibrillation (A-Fib) Summary

Symptoms:
• Palpitations, light-headedness, dizziness, dyspnea, exercise intolerance, chest pain, near-syncope, syncope.

Why?
Cardiac:
	• Valvular heart
typically needed • DOACs ... thrombin inhibitor (dabigatran ... Xa inhibitors (rivaroxaban ... , apixaban, edoxaban ... diagnosis #management #cardiology