7 results
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... #DOAC #Bridging ... Anticoagulant #Anticoagulation ... #Dabigatran #Apixaban ... #Rivaroxaban #Edoxaban
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
Heparin, Fondaparinux ... #Pharmacology #Pathophysiology ... #UFH #DOAC #Dabigatran ... #Apixaban #Rivaroxaban ... NOAC #Mechanism
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Anticoagulants Common ... PCC (Kcentra) - Heparin ... (Praxbind) - Apixaban ... (Lixiana), Rivaroxaban ... #doac #noac #pharmacology
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
Dosing: Apixaban ... #Hematology #Pharmacology ... #Apixaban #Rivaroxaban ... #Dabigatran #Edoxaban ... #NOAC
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
and rivaroxaban ... direct-acting oral anticoagulants ... filtration rate; DOAC ... direct-acting oral anticoagulant ... #DOAC #VTE #Malignancy
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
direct acting oral anticoagulants ... to assess for anticoagulant ... determine timing of DOAC ... ) • Apixaban, Edoxaban ... postoperative #DOAC
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
#pathophysiology ... #anticoagulation ... #anticoagulant ... #Apixaban #Rivaroxaban ... #Edoxaban #heparin