9 results
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
#DOAC #Bridging ... Anticoagulant #Anticoagulation ... #Dabigatran #Apixaban ... #Rivaroxaban #Edoxaban ... #Loading #DVT #Pharmacology
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
PCC (Kcentra) - Heparin ... /LMWH → Protamine ... sulfate - Dabigatran ... (Praxbind) - Apixaban ... #doac #noac #pharmacology
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
DOAC: Cheat Sheet ... - Atrial Fibrillation ... @Bloodman #DOAC ... #Dabigatran #Edoxaban ... #NOAC
Anticoagulant specific factor inhibition. 

#anticoagulation #clotting #INR #heparin #LMWH #NOAC #warfarin #coumadin #rivaroxaban  #Xarelto #apixaban
#anticoagulation ... clotting #INR #heparin ... #LMWH #NOAC #warfarin ... #Pradaxa #management ... #pharmacology #
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
the mainstay of VTE ... accelerates the bridging ... #Heparins #LMWH ... #UFH #DOAC #Dabigatran ... #Fondaparinux #NOAC
Summary table of the mechanism of action, side effect and contraindications of commonly used anti-coagulation drugs.
Molecular Weight Heparin ... (LMWH) - Enoxaparin ... #anticoagulation ... #pharmacology # ... medications #doac
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
filtration rate; DOAC ... anticoagulant; LMWH ... molecular weight heparin ... #DOAC #VTE #Malignancy ... #Management #Hematology
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
recent creatinine clearance ... determine timing of DOAC ... inhibitor) • Apixaban ... , Edoxaban, Rivaroxaban ... postoperative #DOAC
Atrial Fibrillation (A-Fib) Summary

Symptoms:
• Palpitations, light-headedness, dizziness, dyspnea, exercise intolerance, chest pain, near-syncope, syncope.

Why?
Cardiac:
	• Valvular heart
: • Initial heparin ... typically needed • DOACs ... (rivaroxaban, apixaban ... , edoxaban) • Warfarin ... #management #cardiology