9 results
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
#DOAC #Bridging ... Anticoagulant #Anticoagulation ... #Dabigatran #Apixaban ... #Rivaroxaban #Edoxaban ... #Pharmacology #Hematology
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
DOAC: Cheat Sheet ... - Atrial Fibrillation ... OralAnticoagulant #Anticoagulation ... #Hematology #Pharmacology ... #Edoxaban #NOAC
Switching Between Anticoagulants and DOACs
VKA, Dabigatran, Rivaroxaban, Apixaban, Edoxaban, Betrixaban, DOAC, Parenteral anticoagulant

DOI: 10.1161/JAHA.120.017559

#Anticoagulants #DOACs #anticoagulation
VKA, Dabigatran ... Rivaroxaban, Apixaban, Edoxaban ... , Betrixaban, DOAC ... #anticoagulation ... #Switching #hematology
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Protamine sulfate - Dabigatran ... Betrixaban (Bevyxxa), Edoxaban ... PCC (Kcentra) #anticoagulation ... #doac #noac #pharmacology ... #hematology #reversal
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
Currently, edoxaban ... randomized controlled trial ... #DOAC #VTE #Malignancy ... Cancer #Algorithm #Anticoagulation ... #Management #Hematology
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
Pathophysiology Anticoagulation ... the mainstay of VTE ... accelerates the bridging ... Heparins #LMWH #UFH #DOAC ... #Dabigatran #Apixaban
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
**Edoxaban is initiated ... DOAC, direct oral ... #DOAC #VTE #Malignancy ... Cancer #Algorithm #Anticoagulation ... #Management #Hematology
Effect of Direct Oral Anticoagulants on Hemostatic Tests
Horizontal bars correspond to the approximate range of detectability
concentrations of dabigatran ... , apixaban and edoxaban ... thrombin time #doac ... #noac #anticoagulation ... #hematology #laboratory
Atrial Fibrillation (A-Fib) Summary

Symptoms:
• Palpitations, light-headedness, dizziness, dyspnea, exercise intolerance, chest pain, near-syncope, syncope.

Why?
Cardiac:
	• Valvular heart
unknown duration • Anticoagulation ... β-blocker or CCB Anticoagulation ... typically needed • DOACs ... thrombin inhibitor (dabigatran ... rivaroxaban, apixaban, edoxaban