16 results
NOAC / DOAC Pharmacology and Prescribing Cheat Sheet
Novel (or Direct) Oral Anti-Coagulants
 • Rivaroxaban
 • Apixaban
NOAC / DOAC Pharmacology ... Novel (or Direct) Oral ... • Apixaban • Dabigatran ... #NOAC #DOAC #Pharmacology ... management #Direct #Oral
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
of Clearance of Oral ... Hepatic, 25% Renal Dabigatran ... Hepatic, 35% Renal #DOAC ... #NOAC #Metabolism ... Pharmacology #Clearance #oral
Direct-acting oral anticoagulants (DOACs) for VTE treatment and prevention - Comparison Table

#DOAC #Anticoagulants #Anticoagulation #VTE #Management
Direct-acting oral ... anticoagulants (DOACs ... ) for VTE treatment ... Comparison Table #DOAC
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... Clotmaster #VTE #DOAC ... Bridging #Dosing #Oral ... Anticoagulation #Dabigatran
Best practice recommendations for the diagnosis and treatment of adult patients experiencing traumatic brain injury during
diagnosis and treatment ... injury during treatment ... with oral anticoagulants ... Brain #Injury #NOAC ... #DOAC #Management
Oral Anticoagulation Management Cheat Sheet: Warfarin, Apixaban, Dabigatran, Rivaroxaban
 - Mechanism of Action
 - Routine Blood
Oral Anticoagulation ... Warfarin, Apixaban, Dabigatran ... - Resume #Oral ... Anticoagulant #DOAC
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... anticoagulant treatment ... modified factor Xa • Dabigatran ... not available #DOAC ... #Oral #anticoagulant
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
Management of DOACs ... direct acting oral ... interruption per treatment ... of Therapy • Dabigatran ... Perioperative #Management #Treatment
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
algorithm for the treatment ... direct-acting oral ... anticoagulants (DOACs ... filtration rate; DOAC ... direct-acting oral
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
(DOAC interactions ... ) Cancer-treatment ... DOACs are substrates ... metabolization of DOACs ... Dabigatran has moderate