8 results
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Diagnosis Framework ... Hepatopathy • Acute ... Viral Hepatitis ... (>1000): • DILI ... #Diagnosis #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis ... dechallenge • Acute ... disorder (e.g. ascites ... ), Chronic hepatitis ... #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... develops (DIC, ascites ... infiltration) Differential ... Hepatitis, Preeclampsia ... #Pregnancy #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential ... Diagnosis Algorithm ... #differential # ... #hepatology
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
- Alcoholic hepatitis ... fibrosis - Acute ... #Causes #diagnosis ... #differential # ... hepatology #SAAG
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
viral hepatitis ... viral hepatitis ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... Diagnosis Portal ... • Cirrhosis/acute ... hepatitis • Infiltrative ... #hepatology
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis
High albumin gradient (>1.1 g/dl):
 - Cirrhosis	
 - Alcoholic
Diagnosis High ... - Alcoholic hepatitis ... - Massive liver ... Veno-occlusive disease - Acute ... #Diagnosis #hepatology