8 results
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia ... overt cytoplasmic granules ... promyelocytic #leukemia ... #APL #APML #Pathology ... #Hematology #Clinical
Map of proliferative blood disorders. 

By Ariella Coler-Reilly @ariellastudies

#Algorithm #classification #proliferative #blood #disorders #leukemia #hematology #oncology
proliferative blood disorders ... proliferative #blood #disorders ... #leukemia #hematology ... diagnosis #CML #CLL #AML
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... leukemias > 20% ... Chronic leukemia ... distinctive primary granules ... #Hematology #Oncology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
histamine in their granules ... Myeloproliferative Disorders ... Chronic myeloid leukemia ... Acute myeloid leukemia ... Diagnosis #causes #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) • Endocrine disorders ... Antiribosomal P, APLA ... • CAD APLA/LAC ... valve vegetations APLA ... Hodgkin lymphoma and leukemia
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... Neutropenia • Platelet Disorders ... Syndromes #diagnosis #hematology
Helpful Clinical Features in Evaluating Bleeding Disorders
Age of onset
 • Neonate - in 20% of haemophilias,
Evaluating Bleeding Disorders ... relatives (if all ... #Bleeding #Disorders ... #History #peds ... pediatrics #diagnosis #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
• Plasma cell leukemia ... Castleman disease • AL ... Connective tissue disorders ... gastric tumors • Hematology ... : Lymphoma, Leukemia