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acute auer clinical rods smear blood bloodsmear diagnosis hematology lymphoblastic microscopy oncology path pathology pediatrics apml bcell cancer hemepath lbl
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
age • 75% of ALL ... B-cell lineage ALL ... Mature B-cell ALL ... -> AML: Blast crises ... cutaneous plaques) AML
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
(APL) following ... and started on all-trans ... In addition to APL ... AML with maturation ... #APL
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 Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia ... overt cytoplasmic granules ... I see all of these ... promyelocytic #leukemia ... #APL #APML #Pathology
Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
of crystallized granules ... acute myelogenous leukemia ... (AML) that is most ... Microscopy #Auer #Rods #AuerRods ... #AML
Presentation of malignant disease in children Pre-school (<5 years old) - Acute lymphoblastic leukaemia
- (ALL) - peak ... (ALL) - Brain ... (ALL) - Hodgkin ... Presentation #Malignant #Childhood ... #Peds #Pediatrics
B-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma Clinical - Primarily a disease of childhood, 75% <6 yo - Increased
Lymphoblastic Leukemia ... Primarily a disease of childhood ... iAMP21 - BCR-ABL-like ... lauraebrown #BCell #ALL ... Lymphoblastic #Leukemia
Treatment Schema for Standard-Risk Acute Lymphoblastic Leukemia Induction: • Vincristine, Steroid (dexamethasone), L-Asparaginase, Intrathecal (IT) methotrexate Consolidation
Lymphoblastic Leukemia ... Cytarabine #ALL ... Lymphoblastic #Leukemia ... oncology #pediatrics #peds
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