Treatment Schema for Standard-Risk Acute Lymphoblastic Leukemia Induction: • Vincristine, Steroid (dexamethasone), L-Asparaginase, Intrathecal (IT) methotrexate Consolidation & CNS protection: • IT methotrexate, Vincristine, Steroid, Thiopurine Interim and continuing maintenance therapy: • Monthly vincristine and pulsed (5 days), steroid (dexamethasone), Daily 6-mercaptopurine, Weekly oral methotrexate, Prophylactic co-trimoxazole is given throughout treatment (after induction) to prevent Pneumocystis carinii pneumonia, IT methotrexate Delayed intensification: • Vincristine, Dexamethasone, Doxorubicin, L-Asparaginase, IT methotrexate, Cyclophosphamide, Cytarabine #ALL #Acute #Lymphoblastic #Leukemia #Treatment #timeline #oncology #pediatrics #peds #management
