6 results
Presentation of malignant disease in children 
Pre-school (<5 years old) 
 - Acute lymphoblastic leukaemia
ALL) - peak incidence ... leukaemia (ALL) ... leukaemia (ALL) ... Presentation #Malignant #Childhood ... #Peds #Pediatrics
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
: ALL, CML, AML, ... ALL (Acute Lymphoblastic ... -> AML: Blast crises ... cutaneous plaques) AML ... distinctive primary granules
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
(APL) following ... In addition to APL ... (AML) t(8;21), ... Microscopy #Auer #Rods #AuerRods ... #APL
Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
of crystallized granules ... acute myelogenous leukemia ... (AML) that is most ... Microscopy #Auer #Rods #AuerRods ... #AML
B-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma
Clinical
 - Primarily a disease of childhood, 75% <6 yo
 - Increased
Leukemia/Lymphoblastic ... Primarily a disease of childhood ... iAMP21 - BCR-ABL-like ... lauraebrown #BCell #ALL ... #Leukemia #Lymphoma
Treatment Schema for Standard-Risk Acute Lymphoblastic Leukemia
Induction: 
 • Vincristine, Steroid (dexamethasone), L-Asparaginase, Intrathecal (IT) methotrexate
Consolidation
Standard-Risk Acute Lymphoblastic ... Leukemia Induction ... Cytarabine #ALL ... #Leukemia #Treatment ... oncology #pediatrics #peds