8 results
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia ... overt cytoplasmic granules ... I see all of these ... promyelocytic #leukemia ... #APL #APML #Pathology
Assessing and referring childhood cancers #Diagnosis #PrimaryCare #Peds #ChildhoodCancers #ClinicalFeatures #Lymphoma #Wilms #Leukemia #Retinoblastoma #BMJ
and referring childhood ... #PrimaryCare #Peds ... Lymphoma #Wilms #Leukemia
Presentation of malignant disease in children 
Pre-school (<5 years old) 
 - Acute lymphoblastic leukaemia
lymphoblastic leukaemia ... lymphoblastic leukaemia ... lymphoblastic leukaemia ... Presentation #Malignant #Childhood ... #Peds #Pediatrics
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
abundant cytoplasmic granules ... promyelocytic leukemia ... decreased secondary granules ... In addition to APL ... acute myeloid leukemia
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... leukemias > 20% ... Chronic leukemia ... Leukemia): • Lymphocytes ... distinctive primary granules
Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
of crystallized granules ... acute myelogenous leukemia ... (AML) that is most ... Rods #AuerRods #AML
B-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma
Clinical
 - Primarily a disease of childhood, 75% <6 yo
 - Increased
Lymphoblastic Leukemia ... Primarily a disease of childhood ... iAMP21 - BCR-ABL-like ... lauraebrown #BCell #ALL ... Lymphoblastic #Leukemia
Treatment Schema for Standard-Risk Acute Lymphoblastic Leukemia
Induction: 
 • Vincristine, Steroid (dexamethasone), L-Asparaginase, Intrathecal (IT) methotrexate
Consolidation
Lymphoblastic Leukemia ... Cytarabine #ALL ... Lymphoblastic #Leukemia ... oncology #pediatrics #peds