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differential macrocytic workup causes blood cancer cell classification elevatedmcv gap globulin macrocytosis markers mcv mds myelodysplasia myelodysplastic plasmacytoma protein proteingap
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
Approach to Hypoproliferative ... Macrocytic Anemia ... #Anemia #differential ... #diagnosis #algorithm ... #hematology #workup
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... Diagnosis Framework ... by MCV Microcytic ... #MCV #Algorithm ... #hematology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Algorithm Mean ... (BM) ablative disorders ... #Algorithm #Diagnosis ... #Workup #Hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
and Differential Diagnosis ... Algorithm Acute ... anemia - ... #hematology #Markers ... #Algorithm
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Overall Approach ... Diagnosis Algorithm ... • RBC Membrane Disorder ... #Algorithm #Causes ... #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Differential Diagnosis ... Algorithm Normal ... • Small Bowel Disorder ... #Algorithm #Causes ... #Hematology
General Approach to Anemia - Differential Diagnosis Framework 1) Check reticulocyte count to determine if hypo/hyper-proliferative 2) Exclude
General Approach ... to Anemia - Differential ... Diagnosis Framework ... guide further evaluation ... #hematology #algorithm
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... common cytopenia: Macrocytic ... Neutropenia • Platelet Disorders ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
disorder of bone ... • No CRAB - no anemia ... Evaluation? ... #Plasmacytoma #Oncology ... #Hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
first step in evaluation ... Connective tissue disorders ... gastric tumors • Hematology ... #differential #diagnosis ... #hematology
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