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Direct-acting oral anticoagulants (DOACs) for VTE treatment and prevention - Comparison Table

#DOAC #Anticoagulants #Anticoagulation #VTE #Management
Direct-acting oral ... anticoagulants (DOACs ... Table #DOAC ... Anticoagulants #Anticoagulation ... #Table
Summary table of the mechanism of action, side effect and contraindications of commonly used anti-coagulation drugs.
Summary table of ... of action, side effect ... - Dabigatran #anticoagulation ... #medications #doac ... #comparison #table
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
Management of DOACs ... patients on chronic anticoagulation ... available lab test ... per treatment table ... may not require anticoagulation
Effect of Direct Oral Anticoagulants on Hemostatic Tests
Horizontal bars correspond to the approximate range of detectability
Effect of Direct ... on Hemostatic Tests ... thrombin time #doac ... #noac #anticoagulation ... hematology #laboratory #testing
Atrial Fibrillation (A-Fib) Summary

Symptoms:
• Palpitations, light-headedness, dizziness, dyspnea, exercise intolerance, chest pain, near-syncope, syncope.

Why?
Cardiac:
	• Valvular heart
Fibrillation - Testing ... ventricles; to detect ... serum creatinine, test ... typically needed • DOACs ... preferred • Direct
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
event, follow ACC algorithm ... determine if stress test ... Anticoagulation ... surgery Stress Testing ... management for select
Performance Characteristics for Colorectal Cancer Screening Tests
Stool/blood-based tests:
 • FIT: 79% sensitivity, 94% specificity for CRC
Cancer Screening Tests ... Stool/blood-based tests ... specificity for CRC Direct ... #comparison #table ... gastroenterology #CRC #Testing
ACA Colorectal Cancer Screening Guidelines

When to Screen?
When to Stop?
Family History

Performance Characteristics for Colorectal Cancer Screening Tests
Stool/blood-based
Cancer Screening Tests ... Stool/blood-based tests ... specificity for CRC Direct ... #comparison #table ... gastroenterology #CRC #Testing