16 results
Generalized Hyperpigmentation Differentials
Use the Mnemonic "no skin SPARED"

Images from dermnet.nz and merckmanuals

Mnemonic from https://www.medscape.com/slideshow/dermatology-mnemonics-6011359#5 #diagnosis #differential
Hyperpigmentation Differentials ... #5 #diagnosis #differential ... #symptoms #signs ... #dermatology #skin ... #skinrash
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN signs ... Clonus, Babinski’s sign ... • Lhermitte’s sign ... SIGNS/SYMPTOMS ... Signs and symptoms
Clinically Important Vitamins and Vitamin Deficiency States
Fat-soluble Vitamins: 
 • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... Anaemia, neural tube defects ... Vitamins #Deficiency #differential ... #diagnosis #signs ... #symptoms #nutrition
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Diagnosis and Management ... epidermis from dermis Clinical ... Signs/Symptoms/ ... erosions in ~20% Management ... #dermatology
Shawl sign poikiloderma in Dermatomyositis

Poikiloderma in general is a common finding in older individuals with chronic
Shawl sign poikiloderma ... along with other signs ... differentiate it ... RashDecisionz #Shawl #sign ... #Clinical #Photo
Emphysematous Cystitis
Epidemiology:
 • Usually middle-aged diabetic women
 • Other RF: neurogenic bladder, urinary tract outlet obstruction,
immune compromise Clinical ... Signs/Symptoms: ... may have fever/chills ... be present or signs ... also important Management
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... most frequently affects ... Diagnosis: HLH signs ... and symptoms can ... Lymphohistiocytosis #diagnosis #management
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
of UMN and LMN signs ... fasciculations Common Symptoms ... of UMN and LMN signs ... both UMN and LMN signs ... EMG: LMN Signs in
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Paraneoplastic effects ... life-threatening Differential ... test - Cogan sign ... - Peek sign ... Gravis #diagnosis #management
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
• M > F • Affects ... Orange or Hep C Clinical ... with no early symptoms ... Physical Exam/Signs ... workup #oncology #hematology