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diabetes inhibitors dosing summary agonists combo glp1 management medications oral pills renal sglt2 tablets
Diabetes Combination Tablets - Estimated A1c Lowering Metformin + DPP4 • Janumet (metformin + sitagliptin) •
Diabetes Combination ... + DPP4 • Janumet ... Tablets #Oral #DM2 ... #Pharmacology # ... Pills #Endocrinology
DPP-4 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
- Pharmacology ... Recommended to avoid combination ... failure Common Side Effects ... #Summary #DM2 # ... diabetes #endocrinology
Metformin Pharmacology Summary Mechanisms of Action: • Suppresses gluconeogenesis by the liver • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... EricsMedicalLectures/ #Metformin ... #Pharmacology # ... Summary #DM2 #diabetes ... #endocrinology
DPP4 Inhibitors - Normal and Renal Dosing Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
titrate up to effects ... only few side effects ... Renal #Dosing #Pharmacology ... Management #Diabetes #DM2 ... #Endocrinology
SGLT2 Inhibitors SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
Side effects include ... combo product with metformin ... SGLT2 #Inhibitors #Pharmacology ... #Medications #DM2 ... #Diabetes #Endocrinology
GLP-1 Agonists Adlyxin (Lixisenatide) Daily Bydureon (Exenatide ER) Weekly Ozempic (Semaglutide) Weekly Trulicity (Dulaglutide) Weekly Victoza (Liraglutide) Daily
Common side effects ... very similar to DPP4s ... GLP1 #Agonists #Pharmacology ... Dosing #Diabetes #DM2 ... #Endocrinology
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