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diagnosis management hematology rheumatology disease hemophagocytic lymphohistiocytosis signs behcet chagas chronic coronavirus covid19 differential endocrinology glftap hemeonc leukemia lymphocytic macroadenoma
Pediatric Inflammatory Multisystem Syndrome Temporally associated with SARS-CoV-2 infection (PIMS-TS) Clinical features all: fever > 101.3 F most: oxygen
Pediatric Inflammatory ... Multisystem Syndrome ... Clinical features all ... coronavirus #diagnosis #Signs ... #Symptoms
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... most frequently affects ... signs and symptoms ... Low or absent NK cell ... • Bicytopenia Treatment
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• M > F • Affects ... with no early symptoms ... Physical Exam/Signs ... microglobulin Treatment ... • Richter’s Syndrome
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome ... with the HLH syndrome ... Presentation • Common Signs ... and Symptoms: ... Overproduction of pro-inflammatory
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
nervous system • Inflammatory ... • Or brainstem syndromes ... Afferent pupillary defect ... SIGNS/SYMPTOMS ... Signs and symptoms
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
common in Asia • HLA-B51 ... Disease (25-75%): Inflammatory ... Arthritis, AS Treatment ... diagnosis #management #signs ... #symptoms #rheumatology
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
Pituitary Mass Effects ... adenomas that require treatment ... pituitary masses of all ... following order; GH, LH ... Signs / Symptoms
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary Chagas disease (American trypanosomiasis) is an infectious
Chagoma: inflammatory ... Romana's sign ... Indeterminate form (No signs ... /symptoms, positive ... IFA) assays to detect
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... purpura: Strong sign ... CRP GCA (Giant Cell ... • Progressive symptoms ... : Ocular inflammatory
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
all ethnicities ... Symptoms: • ... + Nonspecific symptoms ... chondritis • Inflammatory ... affected tissue Treatment
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