34 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Restrictive lung defect ... lesions Abdominal pain ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
and Symptoms: ... Musculoskeletal: joint ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... #workup
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features
 • RA affects 1% of population, women >
features • RA affects ... pain, swelling, ... pain), especially ... deviation, etc • Systemic ... #symptoms #diagnosis
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... • Differentiate ... #Disease #differential ... #diagnosis #causes ... #hematology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Pain - Diagnostic ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup ... #differential #
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... organ-specific signs ... or symptoms (eg ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
or nerve root Symptoms ... #Pain #MSK #rheumatology ... #approach #workup ... #differential # ... diagnosis #arthritis
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Differential Diagnosis ... noninflammatory Signs ... constitutional symptoms ... weeks) Can Be Caused ... #pain #Differential
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism

In contrast to the
associated with rheumatologic ... presentation of systemic ... life-threatening causes ... #Pericarditis #Symptoms ... #Signs #Presentation
Rare Causes of Abdominal Pain
 • Hereditary Angioneurotic Edema - Recurrent visceral that may by swelling
cardiovascular system ... Positive Carnett's sign ... accompanied by joint ... #differential # ... diagnosis