19 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Multi-system autoimmune disease ... and Symptoms: ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... #workup
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... Afferent pupillary defect ... SIGNS/SYMPTOMS ... Signs and symptoms ... Treatment: •
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
technique used to detect ... context of other symptoms ... /DM), Systemic sclerosis ... ANA #patterns #rheumatology ... #diagnosis #differential
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... glucocorticoid treatment ... organ-specific signs ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
malignancies, Multiple sclerosis ... autoantibodies #signs ... #symptoms #mimickers ... #differential # ... rheumatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
failure PBC Signs ... and Symptoms: ... bile ducts Differential ... cholestasis, Primary sclerosis ... cholangitis #diagnosis #workup
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Presentation: - Disease ... course of the disease ... fasciculations Common Symptoms ... conditions listed in differential ... diagnosis column Treatment
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
meningitis), MCC CNS symptoms ... ) Differential Diagnosis ... Arthritis, AS Treatment ... diagnosis #management #signs ... #symptoms #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
most frequently affects ... age, however the disease ... Diagnosis: HLH signs ... and symptoms can ... #hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Presentation: Systemic Symptoms ... , particularly scleritis ... purpura: Strong sign ... • Progressive symptoms ... #Diagnosis #Rheumatology