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diagnosis hematology signs symptoms gca neurology treatment vasculitis aion algorithm anteriorischemicopticneuropathy arteritis behcet chronic cll common cryoglobulinemia cryoglobulins cvid differential
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Restrictive lung defect ... Demyelinating syndromes ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA) 1) Is visual loss caused
field: altitudinal defect ... Clinical manifestations ... Doppler US : halo sign ... GiantCellArteritis #GCA #Rheumatology ... #Ophthalmology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
(Clinical Dx). ... inhibitors • Uveitis- Ophthalmology ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Hyperviscosity Syndrome ... : • Clinical triad ... • Cryocrit - Detect ... diagnosis #types #classification ... #rheumatology #
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... most frequently affects ... Diagnosis: HLH signs ... Lymphohistiocytosis #diagnosis #management
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Afferent pupillary defect ... patients with clinically ... stimulation Clinical ... sclerosis #diagnosis #management
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Paraneoplastic effects ... Clinical Picture ... test - Cogan sign ... - Peek sign ... Gravis #diagnosis #management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• M > F • Affects ... Orange or Hep C Clinical ... Physical Exam/Signs ... • Richter’s Syndrome ... leukemia • Sezary syndrome
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Affects 1:25,000 ... to 8 years Clinical ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... #diagnosis #management
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
vasculitis) - Affects ... • Cogan Syndrome ... purpura: strong sign ... differential #diagnosis #rheumatology ... #classification
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