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diagnosis differential lupus management comparison erythematosus signs vasculitis antipsychotics autoimmune behcet classification cll closed disease druginduced drugs firstgeneration glaucoma hematology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Lupus (SLE) General ... Restrictive lung defect ... Thrombocytopenia #Lupus #SLE ... #signs #symptoms ... #diagnosis #rheumatology
Glaucoma - Emergency Department Management - All patients should get emergency ophthalmologic consultation - Start with eye drops
with eye drops (see ... add systemic medications ... or refractory symptoms ... is < 40 mmHg #Pharmacology ... #Table
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... months to years) Systemic ... • Evolution: Chronic ... #comparison #table ... #rheumatology #
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... rendering the immune system ... • M > F • Affects ... with no early symptoms ... Physical Exam/Signs
Sedative-Hypnotic Drugs Benzodiazepines: - Bind to specific GABAA receptor subunits at central nervous system (CNS) neuronal synapses
central nervous system ... or withdrawal symptoms ... Hypnotic #Drugs #medications ... #pharmacology # ... comparison #table
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Non-autoimmune rheumatologic ... Induced Lupus: • Symptoms ... with Lupus: • Chronic ... activation and/or medications
First Generation Anti-Psychotics: Mechanisms and Side Effects Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine ACh M1 antagonist - Block
Mechanisms and Side Effects ... VTA -> limbic system ... Extrapyramidal Symptoms ... limbs caused by chronic ... #SideEffects #pharmacology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome Systemic ... Oral aphthae : SLE ... Recurrent and chronic ... diagnosis #management #signs ... #symptoms #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... Symptoms (SX) in ... purpura: Strong sign ... Eosinophilia, asthma, chronic ... Differential #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Eosinophilia, asthma, chronic ... Symptoms (Sx) in ... purpura: strong sign ... vasculitis, and SLE ... differential #diagnosis #rheumatology
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