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diagnosis lupus management oncology leukemia causes chronic cll differential dil disorders erythematosus lymphocytic mds myelodysplasia myelodysplastic platelet signs syndromes systemic
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... pylori test (GI symptoms ... test, ANA (e.g., SLE ... Diagnosis #Causes #Workup ... #hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... • Immunologic Workup ... Lupusreference #druginduced ... #lupus #sle #comparison ... #table #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Systemic Lupus (SLE ... Demyelinating syndromes ... Leucopenia/lymphopenia, Thrombocytopenia ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... with no early symptoms ... Neutropenia, anemia, thrombocytopenia ... Leukemia #diagnosis #workup ... #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... develop leukostasis syndrome ... infiltrates (anemia, thrombocytopenia ... • Tumor lysis syndrome ... #Leukemia #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... age 70 years Symptoms ... platelet count (thrombocytopenia ... Workup: • Complete ... #diagnosis #hematology
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
standing for: - Thrombocytopenia ... erythematosus (SLE ... and the systemic symptoms ... diagnosis #management #rheumatology ... #Thrombocytopenia
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Constitutional symptoms ... is rare in DIL, SCLE-DIL ... • Immunologic Workup ... Lupusreference #DrugInduced ... #Lupus #DIL #rheumatology
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